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Article

The molecular determination of HLA-Cw alleles in the Mandenka (West Africa) reveals a close genetic relationship between Africans and Europeans.

Tissue antigens - 1 Oct 2000

Sanchez-Mazas A, Steiner Q G, Grundschober C, Tiercy J M

Abstract excerpt

HLA-Cw alleles were determined by high-resolution polymerase chain reaction-sequence-specific oligonucleotide probe (PCR-SSOP) oligotyping in a sample of 165 Mandenka, a population from Eastern Senegal previously analysed for A/B and DRB/DQB polymorphisms. A total of 18 Cw alleles were identified, with Cw*0401/5 and 1601 accounting for a combined frequency of 36%. A comparison of Cw allele frequencies among...

Topics

Africa
Alleles
Europe
Genetics, Population
HLA-C Antigens
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11098930
DOI: 10.1034/j.1399-0039.2000.560402.x

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The molecular determination of HLA-Cw alleles in the Mandenka (West Africa) reveals a close genetic relationship between Africans and Europeans.PMID 11098930Read ↗

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