Article
Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?
Laboratory investigation; a journal of technical methods and pathology - 1 Nov 2000
von Zglinicki T, Serra V, Lorenz M, Saretzki G, Lenzen-Grossimlighaus R, Gessner R, Risch A, Steinhagen-Thiessen E
Abstract excerpt
Progressive cerebrovascular atherosclerosis and consecutive stroke are among the most common causes of dementia. However, specific risk factors for vascular dementia are still not known. Human telomeres shorten with each cell division in vitro and with donor age in vivo. In human fibroblasts in v...
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