Article
Collagen type Ialpha1 gene polymorphism in idiopathic osteoporosis in men.
Rheumatology (Oxford, England) - 1 Nov 2000
Peris P, Alvarez L, Oriola J, Guañabens N, Monegal A, de Osaba M J, Jo J, Pons F, Ballesta A M, Muñoz-Gómez J
Abstract excerpt
OBJECTIVE: To analyse the distribution of polymorphism of the collagen type Ialpha1 gene (COL1A1) and its relationship with bone metabolism and bone turnover in men with idiopathic osteoporosis. METHODS: A total of 35 male patients with idiopathic osteoporosis, aged 50.4 +/- 10.3 yr, and 60 healthy males (controls), aged 47 +/- 17 yr, were included in the study. Serum osteocalcin, 25-hydroxyvitamin D and...
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