Reproductive Factors, Subfertility, and Risk of Neural Tube Defects: A Case-Control Study Based on the Oxford Record Linkage Study Register

Abstract excerpt

Periconceptual exposure to subfertility treatments is increasingly common, raising concerns about the possibility of malformations in the offspring. The authors conducted a case-control study to determine whether subfertility or its treatment was associated with increased risk of neural tube defects (NTDs). Cases were 694 women diagnosed with an NTD-affected pregnancy in Oxfordshire or West Berkshire, England,...

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