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Article

Fluctuation of maternal and fetal free extracellular circulatory DNA in maternal plasma

1 Dec 2000

Abstract excerpt

OBJECTIVE: To examine whether concentrations of free extracellular fetal circulatory DNA in maternal plasma are stable or fluctuate. METHODS: Consecutive blood samples were drawn from 13 healthy nonpregnant volunteers and from 16 healthy pregnant women over 3 days. DNA was isolated from the plasma fraction and quantified by real-time polymerase chain reaction (PCR). RESULTS: In nonpregnant controls the total...

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PMID: 11084191
DOI: 10.1016/s0029-7844(00)01065-6

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