Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of single nucleotide polymorphisms in human DNA repair genes.

Carcinogenesis - 1 Nov 2000

Ford B N, Ruttan C C, Kyle V L, Brackley M E, Glickman B W

Abstract excerpt

Variation in gene coding sequence represents a significant factor in predisposition to disease, including cancer. Variants of some DNA repair genes (e.g. MLH1, MSH2 and MSH6) are known to predispose to cancer. We identified single nucleotide polymorphisms (SNPs) in five DNA repair genes in 142 healthy individuals using a DNA sequencing protocol optimized for the direct detection of single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to Cyclin-Dependent Kinases
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endonucleases

Share to O(6)-Methylguanine-DNA Methyltransferase

Share to Protein Serine-Threonine Kinases

Share to Proteins

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 11062157
DOI: 10.1093/carcin/21.11.1977

Genes

CCNH
CDK7
ERCC1
MGMT
MLH1
MSH2
MSH6
XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of single nucleotide polymorphisms in human DNA repair genes.PMID 11062157Read ↗

Polymorphism discovery in 62 DNA repair genes and haplotype associations with risks for lung and head and neck cancers.Semantic proximity Read ↗

Selected technologies for measuring acquired genetic damage in humans.Semantic proximity Read ↗

Gene susceptibility to oxidative damage: from single nucleotide polymorphisms to function.Semantic proximity Read ↗

Genotyping possible polymorphic variants of human mismatch repair genes in healthy Korean individuals and sporadic colorectal cancer patients.Semantic proximity Read ↗

Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans.Semantic proximity Read ↗

Single-nucleotide polymorphisms of mismatch repair genes in healthy Chinese individuals and sporadic colorectal cancer patients.Semantic proximity Read ↗

Mismatch repair detection (MRD): high-throughput scanning for DNA variations.Semantic proximity Read ↗

Splice site mutations in mismatch repair genes and risk of cancer in the general population.Semantic proximity Read ↗

Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing.Semantic proximity Read ↗

Single nucleotide polymorphisms in DNA glycosylases: From function to disease.Semantic proximity Read ↗

Using Somatic Mutations from Tumors to Classify Variants in Mismatch Repair Genes.Semantic proximity Read ↗

Human DNA repair genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.