Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation and chromosome instability in lymphoblastoid cell lines

1 Jan 2000

Abstract excerpt

In order to gain more insight into the relationships between DNA methylation and genome stability, chromosomal and molecular evolutions of four Epstein-Barr virus-transformed human lymphoblastoid cell lines were followed in culture for more than 2 yr. The four cell lines underwent early, strong overall demethylation of the genome. The classical satellite-rich, heterochromatic,juxtacentromeric regions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11060456
DOI: 10.1159/000015641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

DNA methylation and chromosome instability in lymphoblastoid cell linesPMID 11060456Read ↗

EBV transformation and cell culturing destabilizes DNA methylation in human lymphoblastoid cell linesSemantic proximity Read ↗

Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblastsSemantic proximity Read ↗

Long-term Culture of EBV-induced Human Lymphoblastoid Cell Lines Reveals Chromosomal InstabilitySemantic proximity Read ↗

Clonal variation in gene methylation: c-H-ras and alpha-hCG regions vary independently in human fibroblast lineages.Semantic proximity Read ↗

DNA methylation and genetic instability in colorectal cancer cellsSemantic proximity Read ↗

Effects of cellular differentiation, chromosomal integration and 5-aza-2′-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell linesSemantic proximity Read ↗

Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemiaSemantic proximity Read ↗

Alterations in DNA methylation: a fundamental aspect of neoplasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.