Article
The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations.
Twin research : the official journal of the International Society for Twin Studies - 1 Sept 2000
Boomsma D I, Knijff P, Kaptein A, Labeur C, Martin N G, Havekes L M, Princen H M
Abstract excerpt
The effects of apolipoprotein (a), apolipoprotein-E, and apolipoprotein-A4 isoforms on quantitative lipoprotein(a) [Lp(a)] levels were assessed in a sample of 142 Dutch families consisting of two parents and their adolescent twin offspring. A total heritability of 95% was estimated for plasma Lp(a) concentrations. The largest part of this heritability was due to the apo(a) locus which explained 61% of the total...
Topics
- Adolescent
- Algorithms
- Antioxidants
- Apolipoproteins A
- Apolipoproteins E
- Chi-Square Distribution
- Chromosome Mapping
- Genetic Heterogeneity
- Genetic Variation
- Humans