Article
Structural phosphoprotein M2-1 of the human respiratory syncytial virus is an RNA binding protein.
Journal of virology - 1 Nov 2000
Cuesta I, Geng X, Asenjo A, Villanueva N
Abstract excerpt
The structural phosphoprotein M2-1 of human respiratory syncytial virus (HRSV) Long strain shows RNA binding capacity in three different assays that detect RNA-protein complexes: cross-linking, gel retardation, and Northern-Western assays. It is able to bind HRSV leader RNA specifically with cooperative kinetics, with an apparent K(d) of at least 90 nM. It also binds to long RNAs with no sequence specificity. The...
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