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Article

Elevated phenotypic switching and drug resistance of Candida albicans from human immunodeficiency virus-positive individuals prior to first thrush episode.

Journal of clinical microbiology - 1 Oct 2000

Vargas K, Messer S A, Pfaller M, Lockhart S R, Stapleton J T, Hellstein J, Soll D R

Abstract excerpt

Strains of Candida albicans obtained from human immunodeficiency virus (HIV)-positive individuals prior to their first episode of oral thrush were already in a high-frequency mode of switching and were far more resistant to a number of antifungal drugs than commensal isolates from healthy individuals. Switching in these isolates also had profound effects both on susceptibility to antifungal drugs and on the...

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Identifiers

PMID: 11015370
DOI: 10.1128/JCM.38.10.3595-3607.2000
PMCID: PMC87443

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Source receipt: pubmed, retrieved 7 Sept 2026.

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