Article
[From gene to disease; basic concepts].
Nederlands tijdschrift voor geneeskunde - 2 Sept 2000
Breuning M H, Bakker E
Abstract excerpt
The twenty-three pairs of chromosomes in the nuclei of human cells consist of four different components: the nucleotides adenosine, cytidine, guanosine and thymidine. Of this chromosomal DNA, 5% of the nucleotides owing to their sequence code for proteins. This involves first transcription of DNA to messenger RNA (mRNA) following which the coding part is spliced and transported from the nucleus. Translation of...
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