Article
Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma.
The Journal of allergy and clinical immunology - 1 Sept 2000
Christodoulopoulos P, Leung D Y, Elliott M W, Hogg J C, Muro S, Toda M, Laberge S, Hamid Q A
Abstract excerpt
BACKGROUND: We have recently demonstrated an increased number of glucocorticoid receptor-beta (GRbeta)-positive cells in steroid-insensitive subjects with severe asthma. Insensitivity to steroids may be a major contributing factor in fatal asthma; however, no such direct evidence has been report...
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