Article
The mouthwash: a non-invasive sampling method to study cytokine gene polymorphisms.
Journal of periodontology - 1 Aug 2000
Laine M L, Farré M A, Crusius J B, van Winkelhoff A J, Peña A S
Abstract excerpt
BACKGROUND: We describe a simple, non-invasive mouthwash sampling method for rapid DNA isolation to detect cytokine gene polymorphisms. In the present paper, interleukin- 1beta(IL-1B) and interleukin-1 receptor antagonist (IL-1RN) gene polymorphisms were studied. METHODS: Two mouthwash samples and blood samples were collected from 11 healthy individuals. The second mouthwash sample was stored for 7 days at room...
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