Article
Sensitivity of FISH in detection of MLL translocations.
Genes, chromosomes & cancer - 1 Oct 2000
Cuthbert G, Thompson K, Breese G, McCullough S, Bown N
Abstract excerpt
Fluorescence in situ hybridisation (FISH) detection of MLL translocations is now commonplace in cytogenetics laboratories. One of the most widely used probes is the Oncor MLL probe (Oncor, Gaithersburg, MD) that theoretically demonstrates the presence of an MLL rearrangement by a splitting of the FISH signal between the two derivative chromosomes generated by a translocation. Recently, another commercial probe...
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