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Article

Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy.

Antimicrobial agents and chemotherapy - 1 Sept 2000

Bacheler L T, Anton E D, Kudish P, Baker D, Bunville J, Krakowski K, Bolling L, Aujay M, Wang X V, Ellis D, Becker M F, Lasut A L, George H J, Spalding D R, Hollis G, Abremski K

Abstract excerpt

Efavirenz is a potent and selective nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Nucleotide sequence analyses of the protease and RT genes (coding region for amino acids 1 to 229) of multiple cloned HIV-1 genomes from virus found in the plasma of patients in phase II clinical studies of efavirenz combination therapy were undertaken in order to identify the...

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Identifiers

PMID: 10952598
DOI: 10.1128/AAC.44.9.2475-2484.2000
PMCID: PMC90088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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