Article
Genetic identification by mass spectrometric analysis of single-nucleotide polymorphisms: ternary encoding of genotypes.
Analytical chemistry - 15 Jul 2000
Griffin T J, Smith L M
Abstract excerpt
An approach to genetic identification using biallelic single-nucleotide polymorphism (SNP) genetic markers is described in which the three possible genotypes, AA, Aa, or aa, where "A" and "a" represent the two SNP alleles, are assigned a ternary (base 3) digit of 0, 1, or 2, respectively. Genotyping an individual over a panel of separate SNP markers produces a composite ternary genetic code that can be converted...
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