Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD34 Splice Variant: An Attractive Marker for Selection of Gene-Modified Cells

1 May 2000

Abstract excerpt

This study presents a promising selection system for gene-modified cells other than human hematopoietic progenitor and endothelial cells based on transgenic expression of human CD34. Three retrovirally transduced variants of CD34 were compared, differing in the length of their cytoplasmic domains. These were the full-length transmembrane protein (flCD34), a truncated form (tCD34) that is found as a naturally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10933966
DOI: 10.1006/mthe.2000.0068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD34 Splice Variant: An Attractive Marker for Selection of Gene-Modified CellsPMID 10933966Read ↗

CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targetingSemantic proximity Read ↗

Transduction and selection of human T cells with novel CD34/thymidine kinase chimeric suicide genes for the treatment of graft-versus-host disease.Semantic proximity Read ↗

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapySemantic proximity Read ↗

Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer.Semantic proximity Read ↗

Phenotypic, molecular, and functional characterization of human peripheral blood CD34+/THY1+ cells.Semantic proximity Read ↗

Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemiaSemantic proximity Read ↗

An Improved Bicistronic CD20/tCD34 Vector for Efficient Purification and In Vivo Depletion of Gene-Modified T Cells for Adoptive ImmunotherapySemantic proximity Read ↗

Role of CD34 Antigen in Myeloid Differentiation of Human Hematopoietic Progenitor CellsSemantic proximity Read ↗

CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem CellsSemantic proximity Read ↗

High-Throughput Flow Cytometry Purification of Transduced Progenitors Expressing Defined Levels of Vascular Endothelial Growth Factor Induces Controlled Angiogenesis In VivoSemantic proximity Read ↗

Full-length but not truncated CD34 inhibits hematopoietic cell differentiation of M1 cellsSemantic proximity Read ↗

Development of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.