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Article

Placental expression of the nonclassical MHC class I molecule Mamu-AG at implantation in the rhesus monkey

1 Aug 2000

Abstract excerpt

During human implantation trophoblasts mediate attachment of the embryo to the uterine epithelium and invade and reorganize vessels of the maternal endometrium to initiate blood flow to the intervillous space. Expression of the nonclassical MHC class I molecule HLA-G by invading trophoblasts may play a central role in their protection from recognition by the maternal immune system; however, the ontogeny of...

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PMID: 10922066
DOI: 10.1073/pnas.97.16.9104

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Placental expression of the nonclassical MHC class I molecule Mamu-AG at implantation in the rhesus monkeyPMID 10922066Read ↗

Passive Immunization against the MHC Class I Molecule Mamu-AG Disrupts Rhesus Placental Development and Endometrial ResponsesSemantic proximity Read ↗

Identification of a novel MHC class I gene, Mamu-AG, expressed in the placenta of a primate with an inactivated G locus.Semantic proximity Read ↗

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.Semantic proximity Read ↗

The role of HLA-G in human pregnancySemantic proximity Read ↗

The immune-modulating pregnancy-specific glycoproteins evolve rapidly and their presence correlates with hemochorial placentation in primatesSemantic proximity Read ↗

Definitive class I human leukocyte antigen expression in gestational placentation: <scp>HLA</scp> ‐F, <scp>HLA</scp> ‐E, <scp>HLA</scp> ‐C, and <scp>HLA</scp> ‐G in extravillous trophoblast invasion on placentation, pregnancy, and parturitionSemantic proximity Read ↗

HLA-G Isoforms Produced by Placental Cytotrophoblasts and Found in Amniotic Fluid Are Due to Unusual GlycosylationSemantic proximity Read ↗

Adhesion molecules in implantationSemantic proximity Read ↗

Placental Cell Expression of HLA-G2 Isoforms Is Limited to the Invasive Trophoblast PhenotypeSemantic proximity Read ↗

The human amnion is a site of MHC class Ib expression: evidence for the expression of HLA-E and HLA-G.Semantic proximity Read ↗

Expression of major histocompatibility complex (MHC) class 1 molecules on early trophoblast.Semantic proximity Read ↗

Surface Expression of HLA-C Antigen by Human Extravillous TrophoblastSemantic proximity Read ↗

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