Article
Chronic non-spherocytic haemolytic disorders associated with glucose-6-phosphate dehydrogenase variants.
Bailliere's best practice & research. Clinical haematology - 1 Mar 2000
Fiorelli G, Martinez di Montemuros F, Cappellini M D
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect, being present in over 400 million people world wide. In a small number of cases, G6PD deficiency can lead to mild-to-severe chronic haemolysis, which is further exacerbated by oxidative stress. Such G6PD variants have been described all over the world and are responsible for chronic non-spherocytic haemolytic anaemia...
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