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Article

Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme.

Biochemistry - 25 Jul 2000

Araujo M C, Melo R L, Cesari M H, Juliano M A, Juliano L, Carmona A K

Abstract excerpt

Quenched fluorescence peptides were used to investigate the substrate specificity requirements for recombinant wild-type angiotensin I-converting enzyme (ACE) and two full-length mutants bearing a single functional active site (N- or C-domain). We assayed two series of bradykinin-related peptides flanked by o-aminobenzoic acid (Abz) and N-(2,4-dinitrophenyl)ethylenediamine (EDDnp), namely, Abz-GFSPFXQ-EDDnp and...

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Source

Identifiers

PMID: 10913258
DOI: 10.1021/bi9928905

Genes

ACE
FRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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