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Article

Glutamate decarboxylase is not genetically linked to pyridoxine-dependent seizures.

Neurology - 25 Jul 2000

Battaglioli G, Rosen D R, Gospe S M, Martin D L

Abstract excerpt

Several aspects of pyridoxine-dependent seizure (PDS) suggest a mutation affecting glutamate decarboxylase (GAD) as a possible cause. To examine the possibility of GAD linkage with PDS, the authors performed genotype analyses of three families using polymorphic markers near the GAD genes (GAD1 and GAD2). In each family, the affected siblings exhibited different genotypes for the GAD2 gene; in two families the...

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Source

Identifiers

PMID: 10908915
DOI: 10.1212/wnl.55.2.309

Genes

GAD1
GAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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