Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune Response to Recombinant Adenovirus in Humans: Capsid Components from Viral Input Are Targets for Vector-Specific Cytotoxic T Lymphocytes

15 Aug 2000

Abstract excerpt

We previously demonstrated that a single injection of 10(9) PFU of recombinant adenovirus into patients induces strong vector-specific immune responses (H. Gahéry-Ségard, V. Molinier-Frenkel, C. Le Boulaire, P. Saulnier, P. Opolon, R. Lengagne, E. Gautier, A. Le Cesne, L. Zitvogel, A. Venet, C. Schatz, M. Courtney, T. Le Chevalier, T. Tursz, J.-G. Guillet, and F. Farace, J. Clin. Investig. 100:2218-2226, 1997)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10906225
DOI: 10.1128/jvi.74.16.7678-7682.2000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune Response to Recombinant Adenovirus in Humans: Capsid Components from Viral Input Are Targets for Vector-Specific Cytotoxic T LymphocytesPMID 10906225Read ↗

The Challenge for Gene Therapy: Innate Immune Response to AdenovirusesSemantic proximity Read ↗

Immune Recognition of Gene Transfer Vectors: Focus on Adenovirus as a ParadigmSemantic proximity Read ↗

Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving ControversySemantic proximity Read ↗

Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential SolutionsSemantic proximity Read ↗

Cytotoxic T-Lymphocyte Target Proteins and Their Major Histocompatibility Complex Class I Restriction in Response to Adenovirus Vectors Delivered to Mouse LiverSemantic proximity Read ↗

Fully Detargeted Polyethylene Glycol-coated Adenovirus Vectors Are Potent Genetic Vaccines and Escape from Pre-existing Anti-adenovirus AntibodiesSemantic proximity Read ↗

Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy TrialSemantic proximity Read ↗

In Vitro and In Vivo Biology of Recombinant Adenovirus Vectors with E1, E1/E2A, or E1/E4 DeletedSemantic proximity Read ↗

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune responseSemantic proximity Read ↗

Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver.Semantic proximity Read ↗

Immune Responses to AAV in Clinical TrialsSemantic proximity Read ↗

Capsid-Incorporation of Antigens into Adenovirus Capsid Proteins for a Vaccine ApproachSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.