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Identification of a 25-Hydroxyvitamin D3 1α-Hydroxylase Gene Transcription Product in Cultures of Human Syncytiotrophoblast Cells1

1 Jul 2000

Abstract excerpt

Although accumulating data show that placenta is able to synthesize 1,25-dihydroxyvitamin D3, the presence of cytochrome P(450) enzyme capable of converting 25-hydroxyvitamin D3 (250HD(3)) to the biologically active form of vitamin D in this tissue, has not been yet clearly established. In this study, we have investigated the presence of 25-hydroxyvitamin D3 1alpha-hydroxylase (1alpha-(OH)ase) gene expression...

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PMID: 10902806
DOI: 10.1210/jcem.85.7.6693

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