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Article

Genomic Convergence and Suppression of Centrosome Hyperamplification in Primary p53−/− Cells in Prolonged Culture

1 Aug 2000

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10896782
DOI: 10.1006/excr.2000.4916

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Genomic Convergence and Suppression of Centrosome Hyperamplification in Primary p53−/− Cells in Prolonged CulturePMID 10896782Read ↗

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Radiation-Induced Centrosome Overduplication and Multiple Mitotic Spindles in Human Tumor CellsSemantic proximity Read ↗

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Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis.Semantic proximity Read ↗

Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cellsSemantic proximity Read ↗

p53 suppresses structural chromosome instability after mitotic arrest in human cellsSemantic proximity Read ↗

Inhibitory effect of wild-type p53 gene on excessive replication of centrosomes in leukemia cell line K562.Semantic proximity Read ↗

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