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Article

Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans.

Neuron - 1 Jun 2000

Kerr R, Lev-Ram V, Baird G, Vincent P, Tsien R Y, Schafer W R

Abstract excerpt

Electrophysiology and optical indicators have been used in vertebrate systems to investigate excitable cell firing and calcium transients, but both techniques have been difficult to apply in organisms with powerful reverse genetics. To overcome this limitation, we expressed cameleon proteins, genetically encoded calcium indicators, in the pharyngeal muscle of the nematode worm Caenorhabditis elegans. In intact...

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PMID: 10896155
DOI: 10.1016/s0896-6273(00)81196-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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