Article
Sickle cell gene haplotypes in Relli and Thurpu Kapu populations of Andhra Pradesh.
Human biology - 1 Jun 2000
Ramana G V, Chandak G R, Singh L
Abstract excerpt
We performed polymerase chain reaction analysis of 8 restriction-site polymorphisms in the beta-globin gene cluster to define haplotypes and provide hematological profiles of Relli and Thurpu Kapu caste populations in Andhra Pradesh, India. In all sickle cell homozygous subjects, the clinical manifestation of the disease is benign with elevated fetal hemoglobin levels (3.9%-21.1%). Clinical symptoms in some of...
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