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Article

A non-statistical approach to protein mutational variability.

Bio Systems - 1 Jan 2000

Leluk J

Abstract excerpt

The non-statistical, non-Markovian model of protein mutational variability is described. There are presented the essential features of the algorithm of genetic semihomology and some examples of its application. The results of genetic semihomology approach are compared with the results obtained by using statistical algorithms and matrices which are assumed in widely used programs such as ClustalW, FASTA, MultAlin...

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PMID: 10880857
DOI: 10.1016/s0303-2647(00)00074-5

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