Article
Geographic and ethnic distribution of beta-thalassemia mutations in Uttar Pradesh, India.
Hemoglobin - 1 May 2000
Agarwal S, Pradhan M, Gupta U R, Sarwai S, Agarwal S S
Abstract excerpt
We have studied the geographic and ethnic distribution of mutations in 376 subjects who were carriers of beta-thalassemia, and identified the mutations in 365 chromosomes. The majority of the beta-thalassemia carriers were of Uttar Pradesh (India) origin. Their pattern of mutations differed from the other states of India and from those families who had migrated from Pakistan. The frequency of the IVS-I-5 (G-->C)...
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