Distribution of beta-thalassemia mutations in three Asian Indian populations with distant geographical locations.

doi:10.3109/03630269409043620

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Article

Distribution of beta-thalassemia mutations in three Asian Indian populations with distant geographical locations.

Hemoglobin - 1 May 1994

Baysal E, Sharma S, Wong S C, Jogessar V B, Huisman T H

Abstract excerpt

We have identified the beta-thalassemia alleles in 47 pediatric patients with transfusion-dependent thalassemia major from a clinic in New Delhi and in 105 heterozygous relatives. Surprisingly, only five mutations were present in 94 beta-thalassemia chromosomes with frequencies from 10 to 32%. Th...

Topics

Alleles
Base Sequence
Canada
Child
Genetics, Population
Humans
India
Molecular Sequence Data
Mutation
South Africa
beta-Thalassemia

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