Article
Molecular cloning and properties of the chicken leptin-receptor (CLEPR) gene.
Molecular and cellular endocrinology - 25 Apr 2000
Horev G, Einat P, Aharoni T, Eshdat Y, Friedman-Einat M
Abstract excerpt
The mammalian leptin receptor (LEPR) (formerly OB-R) mediates the weight regulatory effects of the circulating hormone leptin. The extreme obese phenotype of recessive mutations in the mouse leptin or LEPR genes (ob/ob and db/db mice, respectively) indicate the high potential of these genes for medical and agricultural research. In this paper, we report on the cloning of the full-length chicken leptin receptor...
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