Article
Molecular identification of main cellular lineages as a tool for the classification of gastric cancer.
Human pathology - 1 May 2000
Sepulveda A R, Wu L, Ota H, Gutierrez O, Kim J G, Genta R M, Graham D Y
Abstract excerpt
Gastric carcinomas (GC) are heterogeneous tumors comprising variable amounts of cells of different lineage phenotype, including gastric mucous cells (surface--SMC or gland--GMC) and intestinal cells (IC). The evaluation of tumor behavior has classically depended on strictly morphological classifications of tumors. Microsatellite instability (MSI) is frequently detected in GC, but whether MSI affects all gastric...
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