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Induction of Fibronectin-Binding Proteins and Increased Adhesion of Quinolone-Resistant<i>Staphylococcus aureus</i>by Subinhibitory Levels of Ciprofloxacin

1 Jun 2000

Abstract excerpt

We recently reported that strain EN1252a, a fluoroquinolone-resistant derivative of Staphylococcus aureus NCTC8325 with mutations in grlA and gyrA, expressed increased levels of fibronectin-binding proteins (FnBPs) and showed a significantly higher attachment to fibronectin-coated polymer surfaces after growth in the presence of subinhibitory concentrations of ciprofloxacin. The present study evaluated the...

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PMID: 10817688
DOI: 10.1128/aac.44.6.1428-1437.2000

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