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Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family.

Arthritis and rheumatism - 1 Apr 2000

Kamatani N, Moritani M, Yamanaka H, Takeuchi F, Hosoya T, Itakura M

Abstract excerpt

OBJECTIVE: Familial juvenile hyperuricemic nephropathy (FJHN, MIM 162000) is an autosomal-dominant disease characterized by underexcretion-type hyperuricemia, gout, and chronic renal failure. No loci responsible for this disease or any underexcretion-type hyperuricemia/gout have ever been identified. The aim of the study was to localize a gene responsible for FJHN by linkage analysis. METHODS: A single large...

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Identifiers

PMID: 10765940
DOI: 10.1002/1529-0131(200004)43:4<925::AID-ANR26>3.0.CO;2-B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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