Article
Detection of mutations in glycoprotein hormone receptors.
Methods (San Diego, Calif.) - 1 May 2000
Gromoll J, Bröcker M, Derwahl M, Höppner W
Abstract excerpt
The luteinizing, follicle-stimulating, and thyroid-stimulating hormone receptors belong to the huge family of G-protein-coupled receptors. Identification of either activating or inactivating mutations of these receptors has led to a fundamental improvement in our understanding of glycoprotein hormone/receptor interaction. Furthermore, clinical phenotypes such as precocious puberty, follicle-stimulating hormone...
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