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Article

Development of Neonatal Th1/Th2 Function

1 Jan 2000

Abstract excerpt

Newborn animals generally mount poor T cell-mediated immune responses in vivo. As a result, neonates fall prey to infectious agents and diseases which have little impact on immunocompetent adult animals. For some time, it was believed that this phenomenon was due to an intrinsic inability of newborns to mount developmentally mature Th1 responses. Recent studies in mice have challenged that view; under certain...

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PMID: 10763707
DOI: 10.3109/08830180009088503

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