Mitochondria and skin disease.

doi:10.1046/j.1365-2230.2000.00605.x

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Article

Mitochondria and skin disease.

Clinical and experimental dermatology - 1 Mar 2000

Birch-Machin M A

Abstract excerpt

In addition to the 3 billion base pair nuclear genome, each human cell contains thousands of copies of a small, 16.5 kb circular molecule of double stranded DNA: mitochondria have their own DNA (mtDNA) which generally accounts for only 1% of the total cellular nucleic acid content. Therefore why should anyone, particularly in the field of dermatology, have an interest in this cytoplasmic organelle and its DNA?...

Topics

Apoptosis
DNA, Mitochondrial
Humans
Mitochondrial Myopathies
Mutation
Skin
Skin Diseases

Source

Open in PubMed

Identifiers

PMID: 10733641
DOI: 10.1046/j.1365-2230.2000.00605.x

Provenance

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