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Role of Adhesins and Toxins in Invasion of Human Tracheal Epithelial Cells by <i>Bordetella pertussis</i>

1 Apr 2000

Abstract excerpt

Bordetella pertussis, the agent of whooping cough, can invade and survive in several types of eukaryotic cell, including CHO, HeLa 229, and HEp-2 cells and macrophages. In this study, we analyzed bacterial invasiveness in nonrespiratory human HeLa epithelial cells and human HTE and HAE0 tracheal epithelial cells. Invasion assays and transmission electron microscopy analysis showed that B. pertussis strains...

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PMID: 10722585
DOI: 10.1128/iai.68.4.1934-1941.2000

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