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Development of Conventional and Real-Time PCR Assays for the Rapid Detection of Group B Streptococci

1 Mar 2000

Abstract excerpt

BACKGROUND: Group B streptococci (GBS), or Streptococcus agalactiae, are the leading bacterial cause of meningitis and bacterial sepsis in newborns. Currently available rapid methods to detect GBS from clinical specimens are unsuitable for replacement of culture methods, mainly because of their lack of sensitivity. METHODS: We have developed a PCR-based assay for the rapid detection of GBS. The cfb gene encoding...

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PMID: 10702518
DOI: 10.1093/clinchem/46.3.324

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