Article
Isolation and characterization of a human neutrophil aggregation defective mutant of Fusobacterium nucleatum.
FEMS immunology and medical microbiology - 1 Mar 2000
Guo M, Reynolds H, Stinson M, De Nardin E
Abstract excerpt
Fusobacterium nucleatum is known to adhere to human polymorphonuclear neutrophils (PMNs) and cause them to aggregate. In this study, we isolated a spontaneously occurring aggregation defective (AGG(-)) mutant and this mutant will be used for future study of the interactions between this bacterium and human PMN. Genomic DNA fingerprinting by random-primed polymerase chain reaction method revealed a difference...
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