Article
Pharmacogenetics of antipsychotic treatment: lessons learned from clozapine.
Biological psychiatry - 1 Feb 2000
Masellis M, Basile V S, Ozdemir V, Meltzer H Y, Macciardi F M, Kennedy J L
Abstract excerpt
The reintroduction of clozapine, the prototype of atypical antipsychotics, in the late 1980s has led to significant advances in the pharmacological management of schizophrenia. Since then, there has been a rapid development of novel "atypical" antipsychotic agents that have been pharmacologically modeled, to a certain extent, after their predecessor clozapine. As with all antipsychotics, there is variability...
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