Article
The human PEX3 gene encoding a peroxisomal assembly protein: genomic organization, positional mapping, and mutation analysis in candidate phenotypes.
Biochemical and biophysical research communications - 24 Feb 2000
Muntau A C, Holzinger A, Mayerhofer P U, Gärtner J, Roscher A A, Kammerer S
Abstract excerpt
In yeasts, the peroxin Pex3p was identified as a peroxisomal integral membrane protein that presumably plays a role in the early steps of peroxisomal assembly. In humans, defects of peroxins cause peroxisomal biogenesis disorders such as Zellweger syndrome. We previously reported data on the human PEX3 cDNA and its protein, which in addition to the peroxisomal targeting sequence contains a putative endoplasmic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.