Epidemiology, biochemistry and evolution of Trypanosoma cruzi lineages based on ribosomal RNA sequences

Abstract excerpt

A puzzle in Chagas disease research has been to correlate molecular markers with epidemiology since isolates of Trypanosoma cruzi exhibit a broad host range, induce distinct clinical presentations in patients and show great diversity in biological and biochemical characteristics. Early studies on population genetics revealed substantial isozymic variability among isolates of T. cruzi defining three major groups...

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