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Article

Single cell detection of inherited retinoblastoma predisposition.

Prenatal diagnosis - 1 Dec 1999

Sütterlin M, Sleiman P A, Onadim Z, Delhanty J

Abstract excerpt

Retinoblastoma susceptibility is an autosomal dominantly inherited cancer predisposition which also confers a life-long increased risk for various non-ocular malignancies. We developed a protocol for single cell detection of this disorder which enables its preimplantation genetic diagnosis as an alternative to prenatal diagnosis with attendant pregnancy termination. The presented method detects the underlying...

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PMID: 10660960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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