Mitochondrial defects in cardiomyopathy and neuromuscular disease.

Abstract excerpt

Over the past 11 years, a considerable body of evidence has accumulated implicating defects in the mitochondrial energy-generating pathway, oxidative phosphorylation, in a wide variety of degenerative diseases including myopathy and cardiomyopathy. Most classes of pathogenic mitochondrial DNA mutations affect the heart, in association with a variety of other clinical manifestations that can include skeletal...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aging
• Share to Cardiomyopathies
• Share to Energy Metabolism