Article
Protein-protein interaction of FHL2, a LIM domain protein preferentially expressed in human heart, with hCDC47.
Journal of cellular biochemistry - 1 Jan 2000
Chan K K, Tsui S K, Ngai S M, Lee S M, Kotaka M, Waye M M, Lee C Y, Fung K P
Abstract excerpt
In the yeast two-hybrid library screening, the heart-specific FHL2 protein was found to interact with hCDC47. In vitro interaction study between FHL2 protein and hCDC47 was demonstrated. From the results of domain studies by the yeast two-hybrid assay, the second and third LIM domains in conjunction with the first half LIM domain of FHL2 were identified to be important in binding with hCDC47. Besides, in Northern...
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