[Experimental verification of the results of the mathematical modeling of the process of formation of alpha-amylase-nonproductive mutants of Bacillus subtilis under continous cultivation].

Abstract excerpt

When Bacillus subtilis produces alpha-amylase in the course of continuous cultivation, it is difficult to maintain the activity at a constant level. This may be due to the formation of nonproductive mutants. Individual cells in the population have been analysed in the course of the continuous process. The composition of the population changes depending on time and the composition of the growth medium....

Topics

• Amylases
• Bacillus subtilis
• Culture Media
• Enzyme Activation
• Enzyme Induction
• Models, Biological
• Mutation
• Selection, Genetic
• Time Factors
• alpha-Amylases