Article
Meta-analysis of linkage studies.
Genetic epidemiology - 1 Jan 1999
Badner J A, Goldin L R
Abstract excerpt
Lander and Kruglyak [1995] gave guidelines for interpreting linkage results based on estimating how often a particular threshold for significance would be exceeded by chance in a single genome scan. What is unknown is how often two or more genome scans would exceed a particular threshold within the same region. We develop theoretical estimates of these values and compare these with the empirical estimates derived...
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