Article
Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridization.
The American journal of pathology - 1 Dec 1999
Girard J P, Baekkevold E S, Yamanaka T, Haraldsen G, Brandtzaeg P, Amalric F
Abstract excerpt
High endothelial venules (HEVs) are specialized postcapillary venules, found in lymphoid organs and chronically inflamed tissues, that support high levels of lymphocyte extravasation from the blood. Molecular characterization of HEV endothelial cells (HEVECs) has been hampered by difficulties in their purification and in vitro maintenance. To overcome these limitations, we developed a strategy combining the use...
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