Article
Extensive interplasmidic duplications change the virulence phenotype of the relapsing fever agent Borrelia turicatae.
Molecular microbiology - 1 Dec 1999
Penningon P M, Cadavid D, Bunikis J, Norris S J, Barbour A G
Abstract excerpt
The relapsing fever agent Borrelia turicatae has two antigenically distinct serotypes, A and B, which differ in their variable small proteins (Vsps) and in their degree of virulence and neurotropism in mice. Each Vsp gene (vspA or vspB) had an expression-linked copy that was unique to the serotype expressing it. This was located on one linear plasmid, which was defined by the upstream sequence. The archived...
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