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Article

Progesterone Directly and Indirectly Affects Perforin Expression in Cytolytic Cells

1 Nov 1999

Abstract excerpt

PROBLEM: Decidual lymphocytes (DL) expressing the cytolytic molecule perforin represent approximately 55% of DL in the first trimester of human pregnancy. Progesterone dominates this phase of pregnancy and controls the production of uterine cytokines and growth factors. The aim of this study was to investigate the role of progesterone and progesterone-induced blocking factor (PIBF) on perforin expression in DL...

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Share to Preterm Birth and Chorioamnionitis
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PMID: 10584987
DOI: 10.1111/j.1600-0897.1999.tb00107.x

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